I was replying the message for my friend, ioritree.
He said he just put the file under exefs_patches\es_patches ,,, no need to reboot.
BTW, he uses atmosphere to test it.
hope his reply helps you.
I also got the same error: run time error '6' Overflow
Windows 10 64bit , using administrator mode, EmuTool 0.2.6
Thanks so much for making this awesome tool, hope the problem could be solved soon.
I may try the new ram site, and download more RAM to my Switch. Not sure if ddr3 is the right ram
for it tho. Edit- no it uses floppy Ram, just like @AncientBoi