I tried it with USB Loader GX and I still had the same problem, I heard people had experienced the same problem with the game in USB Loader GX aswell but they were not using discs.
I recently purchased a physical official copy of Go Vacation NTSC and wanted to try it on my softmodded Japanese Wii. I have the Priiloader region free hacks installed already. I tried booting it through disc channel, the disc booting screen started but when I clicked start my wiimote...
I may try the new ram site, and download more RAM to my Switch. Not sure if ddr3 is the right ram
for it tho. Edit- no it uses floppy Ram, just like @AncientBoi